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African Americans | General | Allen-McFarland Family Papers |
| Business | Maco Beauty College Collection |
| Education | Immanuel Lutheran College Collection |
| | Abraham H. Peeler Papers |
| Politics | Bert Hall Papers (20th cent.) |
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Architecture | Bumpass House (Greensboro) | Troy-Bumpass Papers |
| Dunleith (Greensboro) | Dick Family Papers |
| Rose Villa (Greensboro) | Alford-Eckel Family Papers |
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Business/Industry | Greensboro | Benjamin Cone Papers (20th cent.) |
| | Houston Family Papers (19th-20th cent.) |
| | Jefferson Standard Life Insurance Co. Collection (20th cent.) |
| | William Kerr Papers (19th cent.) |
| | Lindley Nurseries Collection (19th-20th cent.) |
| | Richardson-Vicks Collection (19th-20th cent.) |
| | Vick Chemical Co. Collection (20th cent.) |
| Guilford County | Anthony Family Papers (19th-20th cent.) |
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Education | General | Frances Eshelman Papers (20th cent.) |
| | John D. Hodges Papers (19th-20th cent.) |
| African Americans | Abraham H. Peeler Papers |
| Nursing | Mabel Hayes Boettger Papers (1920s) |
| | Jean Payne Rabie Family Papers |
| Virginia: Sweet Briar College | Lindley Family Papers |
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Greensboro | ca. 1900 | Charles R. Abbott Papers |
| | City of Greensboro Collection |
| | James Turner Morehead Family Papers |
| 1930s | Alford-Eckel Family Papers |
| 19th Century | Faulconer/Lindsay Family Papers |
| | Mitchell Family Papers |
| | Jacob Henry Smith Family Papers (19th-20th cent.) |
| 20th Century | Fielding Fry Papers |
| | McDaniel Lewis Papers |
| | Fred Ratledge Papers |
| | Jacob Henry Smith Family Papers (19th-20th cent.) |
| Parks & Recreation | Oka T. Hester Family Papers (20th cent.) |
| Real Estate | Basil J. Fisher Papers (ca. 1903. Re: Fisher Park) |
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Guilford County | 19th Century | Anthony Family Papers (19th-20th cent.) |
| | Donnell Family Papers |
| | Andrew Gibson Papers |
| | Mitchell Family Papers |
| 20th Century | Anthony Family Papers (19th-20th cent.) |
| | Guilford County Collection |
| | Fred Ratledge Papers |
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Law Enforcement | 20th Century: Prohibition | Fred Ratledge Papers |
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Literature | O. Henry | Alexander W. McAlister Collection |
| | Earley W. Bridges Collection |
| | Paul S. Clarkson Collection |
| | Roberta Porter Hon Collection |
| | William Sidney Porter Papers |
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Medicine | Civil War | Plunkett Collection |
| Physicians | Arthur E. Ledbetter Register |
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Military | Guilford Battleground | Guilford Battleground Company Collection |
| Spanish-American War | Charles R. Abbott Papers |
| Civil War | Civil War Collection |
| | Edward A. Small Family Papers |
| World War I | William P.D. Bush Papers |
| | Susanne B. Hoskins Papers |
| World War II | William P.D. Bush Papers |
| | Doug Dickerson Papers |
| | Luis Felicia Papers |
| | Ned Harrison Collection |
| | McDaniel Lewis Papers |
| | Stephen P. Millikin Papers |
| | Puckett Family Papers |
| | Francis Edgar Thomas Papers |
| | Col. Paul Younts Papers |
| Vietnam War | Joseph Gruendler Papers |
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Politics | Greensboro | Benjamin Cone Papers (20th cent.) |
| | Fielding Fry Papers (1940s) |
| | Bert Hall Papers (20th cent.) |
| | John D. Hodges Papers (19th-20th cent.) |
| | McDaniel Lewis Papers (20th cent.) |
| | Ralph L. Lewis Papers (20th cent.) |
| | William L. Trotter Jr. Family Papers (1960s) |
| North Carolina | Thomas Settle III Papers (19th-20th cent.) |
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Slavery | Guilford County | Mitchell Family Papers (1830s-50s) |
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Sports | Baseball (Greensboro) | Walter Hammersley Papers (1908+) |
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Vandalia, N.C. | | Anthony Family Papers (19th-20th cent.) |
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Women | Education | Frances Eshelman Papers (20th cent.) |
| | Anne Parham Papers |
| Guilford County | Anthony Family Papers (19th-20th cent.) |
| Nursing | Mabel Hayes Boettger Papers |
| | Susanne B. Hoskins Papers |